Oral antibiotics may be prescribed in more severe or widespread cases of impetigo. Unlike topical treatments, oral antibiotics work throughout the body and can be more effective when the infection is extensive or not responding to initial treatment.

Maintaining good hygiene practices is also important to help reduce the spread of infection. This includes regular hand washing, avoiding scratching affected areas, and not sharing towels, clothing, or bedding with others. Over-the-counter pain relief medication may also help manage discomfort where needed.

In some cases, follow-up consultations may be recommended if symptoms persist or standard treatments are not proving effective. For more complex or severe infections, a referral to a specialist may be required for further assessment and treatment.

The condition is also more prevalent in warm and humid environments, where bacteria can thrive more easily. In addition, people with existing skin conditions such as eczema, psoriasis, or dermatitis may be at greater risk, as damaged or irritated skin can make it easier for bacteria to enter and cause infection.

Other factors that may increase the risk of developing impetigo include close physical contact, crowded environments such as schools or nurseries, and cuts, insect bites, or other breaks in the skin.